Brad

anime charater
 * The first season of  Asura Cryin' : although the heroes successfully foiled Kagakagari's evil schemes, the Big Badtook a Villain: Exit, Stage Left, and got away scot-free while leaving our heroes bereft of their most valuable asset.
 * Berserk 's anime adaptation does not end well at all for anyone except the bad guys. Griffith goes evil in a big way and becomes the fifth member of the Godhand, Femto. He throws his former friends, the Band of the Hawk, to the wolves as they get eaten by monsters straight out of nightmares, and then, as his very first act upon becoming Femto, rapes Casca to insanity right in front of Guts, with Guts losing a hand and eye to demons and being powerless to do anything about any of the above. The manga continues on from that point, and the point where the anime ends is just before the Skull Knight shows up to pull Guts and Casca out of the fire before Griffith and the others can finish them off.
 * The one true constant in  Black Lagoon, since  everybody  is a villain, and in Rock's case, becomes one (he still wants to help people, but technically he becomes a villain since he joins and cooperates with villains).
 * That said, the show's  antagonists  seldom win. Although the crew is villainous, they usually do the job they're hired to do without fail. The closest thing the show has gotten to this trope is the Fujiyama Gangsta Paradise arc, in which Rock fails at saving Yukio, Ginji stops trying to be a better person and is subsequently killed by Revy, while Balalaika sweeps the board and dismantles the Washimine Clan and successfully backstabs her erstwhile allies, while disillusioning Rock on top of it.]] Unusual in that the 'Big Bad' was still technically The Hero's  employer ...
 * Near the end of  Casshern Sins, Dio (probably the closest thing the series has to a proper villain) finally succeeds in defeating Invincible Hero Casshern. Fortunately, by the end of the series, this is all he cared about doing, so he just wanders off and waits for the Ruin to kill him afterwards.
 * The anime version of  Chrono Crusade . The protagonists (Azmaria) all die and the villain survives and partially realizes his Evil Plan.
 * The ending of the first season of  Code Geass, the finale ends with a Britannian victory, though a Pyrrhic one, and the deaths of several Black Knights, including main members, and the incarceration of the survivors, and with the main hero, as revealed in the Oddly Named Sequel, captured, having his memories erased.
 * By definition, this is going to be true of Code Geass' spin-off, Akito the Exiled. As Akito is part of the EU forces, which are canonically defeated and conquered by Britannia both offscreen, and quite early, in Code Geass R2. Not to mention the appearance of Suzaku.
 * Dai Mahou Touge . The main character, Punie Tanaka, is a Villain Protagonist who is sent to Earth from an alternate dimension as a test to check if she is adequate to be the heir to her parents' despotic and dystopian kingdom. During the course of the series, rebels and jealous sisters try to eliminate her. They all fail horribly, and Punie passes the test with flying colors.
 * #badboy ;)